‘Miracle poison’ for novel therapeutics

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Researchers prove they can engineer botulinum toxin proteins to find new targets with high selectivity, a critical advance toward potential new treatments for everything from neuroregeneration to cytokine storm
When people hear botulinum toxin, they often think one of two things: a cosmetic that makes frown lines disappear or a deadly poison.
But the “miracle poison,” as it’s also known, has been approved by the F.D.A. to treat a suite of maladies like chronic migraines, uncontrolled blinking, and certain muscle spasms. And now, a team of researchers from Harvard University and the Broad Ins

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